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Research

Research

We develop catalytic systems and reaction platforms that can control reactivity and selectivity of abundant feedstock molecules, enabling the efficient synthesis of societally important nitrogen-containing compounds, including those central to human health, advanced materials, and sustainable technologies.
We focus on synthesis, catalysis, and mechanistic studies as the foundation of our mechanism-guided reaction design.

Hover over each section for details!

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Synthesis

We design and synthesize a wide variety of substrates and catalysts based on mechanistic hypotheses.

By systematically exploring structure–reactivity relationships, we drive the discovery and optimization of new reactions.

Catalysis

We explore new modes of catalysis through projects in both organocatalysis and transition-metal catalysis. Our goal is to uncover catalytic systems that offer high efficiency, selectivity, and practical utility in synthesis.

We employ spectroscopic and computational techniques to elucidate reaction mechanisms and key molecular interactions. These mechanistic insights inform the design of reactions and catalysts.

Mechanistic studies

feedstock molecules
cat.
valuable
N-molecules
selective C–N bond formation 
Lab Photos

Lab Photos

In addition, we benefit from access to NMR, MS, and X-ray facilities!

University of Illinois Urbana-Champaign

361 Roger Adams Laboratory

600 S. Mathews Avenue

Urbana, IL 61801

misomura [at] illinois.edu

(217) 300-2319

​© 2026 Isomura Lab

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